Đánh giá hiệu suất chiết và tác dụng kháng khuẩn từ cao chiết của một số loài dược liệu phân bố tại rừng ngập mặn Xuân Thủy, Nam Định

Abstract

Objectives: This study aimed to evaluate the extraction efficiency and antibacterial ability of methanol (MeOH) extracts from 12 medicinal plants.

Subjects and methods: Leaves of 12 medicinal plants were collected in May and July 2023 in Xuan Thuy National Park. They were isolated using methanol with ultrasonic assistance. The obtained extracts were investigated for antibacterial activity against 6 bacterial strains and 01 yeast strain.

Results: The total extraction yields of methanol (MeOH) from 12 medicinal plants ranged from 4.5 - 28.4% extracts. The highest MeOH extraction yields were extracted from Aegicera corniculatum (28.4%), Rhizophora stylosa (28.1%), Kandelia candel (27.5%), Sonneratia caseolaris (19.5%). Meanwhile, MeOH extraction yields were lower in Sphaneticola trilobata and Lumnitzera racemosa with 4.8% and 4.5%, respectively. The antibacterial activity investigation results revealed that Sonneratia apetala and Sonneratia caseolaris had the highest inhibitory activities at 320 mg/mL. Other medicinal plants had lower antibacterial activities against all strains at concentrations ranging from 640 - 1280 µg/mL.

Conclusions: The total efficiency of methanol extracts of 12 medicinal plants varied between 4,5 – 28,4%. Total extractions from Sonneratia apetala and Sonneratia caseolaris are highest inhibited the growth of Salmonella enterica at the MIC = 320 mg/mL.