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Ngày xuất bản: 15/06/2023
Số lượt xem tóm tắt: 35
Số lượt xem PDF: 17
DOI: https://doi.org/10.60117/vjmap.v50i3.221
Số xuất bản
Tập 50 Số 3 (2023)
Chuyên mục
Bài nghiên cứu
Trích dẫn bài báo
Doan, M. T., Ha, Q. P., Nguyen, H. N., Pham, H. T., Quach, T. Y., Lu, D. H. M., Tran, D. S., Pham, N. T., & Dang, T. L. P. (2023). Effects of Thuocnamtieuu: a Study in Mice Model of Induced Colorectal Tumors. Tạp Chí Y Dược cổ truyền Việt Nam, 50(3), 73-80. https://doi.org/10.60117/vjmap.v50i3.221

Effects of Thuocnamtieuu: a Study in Mice Model of Induced Colorectal Tumors

Doan Minh Thuy1, Ha Quang Phong1, Nguyen Hoang Ngan2, Pham Huyen Trang1, Quach Thi Yen1, Lu Doan Hoat Muoi1, Tran Dinh Sinh1, Pham Ngoc Tien1, Dang Thi Lan Phuong1,
1 1 Vietnam University of Traditional Medicine
2 Vietnam Military Medical University

Nội dung chính của bài viết

Tóm tắt

Objectives: The present study was undertaken to evaluate the effects of Thuocnamtieuu in AOM/ DSS-induced-colorectal tumors mice.


Subject and method: 48 six-week-old Swiss mice were randomly divided into 06 groups. Two doses of Thuocnamtieuu were administered via intragastric gavage to Swiss mouse with AOM/ DSS induced colorectal tumours. After 28 days treatment, all mice were sacrified. Assessment of the number and size of colorectal tumours, histopathological analysis were performed.


Results: The data have shown that Thuocnamtieuu has been effective in reducing significantly tumor volume (both benign and cancerous), but had not significantly decreased the number of tumors, reducing significantly the number of abnormal cells (cellular pleomorphism, Langerhang cells) in experimental colorectal cancer mice when compared to the control ones.


Conclusions: Thuocnamtieuu have the effect of reducing the colorectal tumors in a AOM/DSSinduced-colorectal tumors mice.

Chi tiết bài viết

Từ khóa

Colorectal tumour, Thuocnamtieuu, AOM/DSS.

Tài liệu tham khảo

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