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Date Published:
05/01/2021
Abstract Views: 60
Views PDF: 59
Views PDF: 59
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Section
Research Articles
How to Cite
Tôn, M. C., Nguyễn, T. B., Trương, V. B., & Nguyễn, H. N. (2021). Acute Toxicity And Effect In Hematologic Functions Of Linh Que Truat Cam Thang - Nhi Tran Thang Capsules. Viet Nam Journal of Traditional Medicine and Pharmacy, 34(1), 48-52. https://doi.org/10.60117/vjmap.v34i1.126
Acute Toxicity And Effect In Hematologic Functions Of Linh Que Truat Cam Thang - Nhi Tran Thang Capsules
Main Article Content
Abstract
To ensure the safety of Linhquetruatcamthang-Nhitranthang before conducting effective studies of the formular for the treatment of dyslipidemia. We carried this study with aims: Evaluate acute toxicity and effect in hematologic functions in experimental animals of LQTCT-NTT.
Results and conclusions: LQTCT-NTT has not acute toxicity in the maximum dose of 12,0g in experiment (25 times higher than the clinical dose) and LQTCT-NTT has not impacts on hematologic functions of experimental animals at dose 0.28g/kg BW and dose 0.84g/kgBW, oral for 90 days.
Article Details
Keywords
Dyslipidemia, Linh que truat cam thang - Nhi tran thang capsule.
References
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2. Abrham W.B. (1978 ): Techniques of Animal and Clinical ToXicology, Med. pub. Chicago, pp 55 - 68.
3. WHO (1993): Research Guidelines for Evaluating the Safety and Efficacy of Herbal Medicines, Manila, Philipin, pp 35 - 41.
4. OECD (2001). Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Humane Endpoints for EXperimental Animals Used in Safety Evaluation, acute oral toXicity. Environmental Health and Safety Monograph Series on Testing and Assesment No 19.
5. World Health Organization (2000), Working group on the safety and efficacy of herbal medicine, Report of regional office for the western pacific of the World Health Organization.
6. Đỗ Trung Đàm (2006), Phương pháp nghiên cứu tác dụng dược lý của thuốc từ dược thảo, NXB Khoa học và Kỹ thuật Hà Nội, tr. 335- 42, 347-52, 355-368, 377-392.