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Date Published: 10/03/2021
Abstract Views: 88
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DOI: https://doi.org/10.60117/vjmap.v35i2.132
Issue
Vol. 35 No. 2 (2021)
Section
Research Articles
How to Cite
Phạm, T. V. A., Đinh, T. T. H., Phạm, V. T., Trần, Q. M., & Nguyễn, D. T. (2021). Study the sub-chronic toxicity of Ha Giang allium sativum extract on experiment. Viet Nam Journal of Traditional Medicine and Pharmacy, 35(2), 4-11. https://doi.org/10.60117/vjmap.v35i2.132

Study the sub-chronic toxicity of Ha Giang allium sativum extract on experiment

Thị Vân Anh Phạm, Thị Thu Hằng Đinh, Văn Tú Phạm, Quang Minh Trần, Duy Thuần Nguyễn

Main Article Content

Abstract

Objectives: The research evaluated the sub-chronic toxicity of Ha Giang black garlic (Allium Sativum) extract through oral administration in animal experiment. The sub-chronic toxicity study was conducted by the recommendation of WHO in rats with oral doses of 0.4 g/kg/day and 2.0 g/kg/day in 4 consecutive weeks. As a result, oral administration of black garlic extract at the doses of 0.4 g/kg/day and 2.0 g/kg/day had no effect on general condition, body weight, hematological parameters, hepato-renal functions and histopathological structures of liver and kidney. In conclusion, black garlic extract did not appear to produce sub-chronic toxicity in rats.

Article Details

Keywords

Black garlic, sub-chronic toxicity, rat.

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