Study The Sub-Chronic Toxicity Of “Bach Phu Thang” On Experiment

Văn Bảo Nguyễn, Duy Thuần Nguyễn, Mạnh Cường Lê, Minh Sơn Dương, Thị Vân Anh Phạm, Thị Thu Hằng Đinh

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Abstract

Objectives: The research evaluated the sub-chronic toxicity of “Bach phu thang” through oral administration in animal experiment. The sub-chronic toxicity study was conducted by the recommendation of WHO in rats with oral doses of 11.4 g/kg/day and 22.8 g/kg/day in 4 consecutive weeks. As a result, oral administration of “Bach phu thang” at the doses of 11.4 g/kg/day and 22.8 g/kg/day had no effect on general condition, body weight, hematological parameters, hepato-renal functions and histopathological structures of liver and kidney. In conclusion, “Bach phu thang” did not appear to produce sub-chronic toxicity in rats.

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