Evaluation of the influence of Dong trung ha thao banikha capsules on liver and kidney function in experimental rats

Thị Vân Anh Phạm, Thị Thu Hằng Đinh, Thị Hồng Gấm Nguyễn, Thị Hồng Nguyễn, Thị Thương Nguyễn, Minh Sắt Lê, Duy Thuần Nguyễn

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Abstract

Objectives: The research evaluated the influence of Dong trung ha thao Banikha capsules on liver and kidney function of experimental rats.


Subjects and methods: Rats was given continuous oral administration of Dong trung ha thao BANIKHA capsules at doses of 0.39 g/kg and 1.16 g/kg during 4 weeks. Hepato-renal toxicity was assessed before the experiment, after 2 weeks and 4 weeks of taking capsules. Micro-histological images of liver and kidney were obtained at the end of the experiment.


Results: The research showed that Dong trung ha thao BANIKHA capsules at doses of 0.39 g/kg and 1.16 g/ kg taken continuously during 4 weeks had no effects on serum levels of AST, ALT, total bilirubin, total cholesterol, albumin, creatinine and micro-histological images of liver and kidney.

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