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Assess the sedative effect of Ich khi an than - HVY tablets on experimental
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Abstract
Objectives: The study was conducted to assess the sedative effects of Ich khi an than – HVY tablets on experimental animals.
Subjects and methods: Sedative effect: Use 4 models: Rotarod rotary shaft (Shiotsuki H. and et al); Measure signed activity (Mill J. and et al); Advanced plus sign (G. Olayiwola and et al); Causing seizures with nikethamid (Wu X.Y. and et al).
Results: The sedative effect of the Ich khi an than - HVY is confirmed by empirical evidence: reduced cling time on Rotarod rotary shaft; reduce the times of vertical and horizontal movements on the signed activity model; increasing the times of closed and open branches saved on the advanced plus sign model; prolonging the onset of convulsions and the time mice died after nikethamid injection were different with the biological control lot and the time before using the reagent (p<0,05).
Conclusions: The sedative effect is similar to Diazepam 5mg at a dose of 1.44 tablets/kg/day and 4.32 tablets/kg/day.
Article Details
Keywords
Ich khi an than, HVY, experimental
References
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