Outcomes of concurrent chemoradiotherapy in patients of stage iii adenocarcinoma of the lung

Thế Cường Trịnh, Thị Thái Hòa Nguyễn

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Abstract

Objects: To evaluate of concurrent pemetrexed-cisplatin and thoracic radiation therapy in patients with stage III adenocarcinoma of the lung.


Subjects and methods: The cross-sectional study was conducted on 31 patients diagnosed stage III lung adenocarcinoma, treated by pemetrexed-cisplatin regimen combined thoracic radiation therapy at Vietnam national cancer hospital from 3/2018 to 8/2020.


Results: Of our 31 patients, overall response rate and disease control accounted for 54,8% and 90,3% respectively. Toxicities are mainly grade 1, 2.


Conclusion: Pemetrexed-cisplatin combined with thoracic radiation therapy has a high response as well as high control disease rate, good patient tolerance and less common side effects at grade 3, 4.

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