Article Sidebar
Views PDF: 8
Studying the pain reducing, anti-inflammatory effects of liquid extract xuong khop nam thang on experiment
Main Article Content
Abstract
Objective: Evaluate the analgesic and anti-inflammatory effects of Xuong khop nam thang liquid extract in experiments.
Subjects and methods: Research on the analgesic effect of Xuong khop nam thang liquid extract on 02 models: Research on the central analgesic effect using the "hot plate" method and Research on the peripheral analgesic effect according to the cramping pain model using acetic acid. Research on anti-inflammatory effects on 02 models: Research on acute anti-inflammatory effects on the mouse paw edema model using Carrageenin and research on chronic anti-inflammatory effects using the granuloma model.
Results: With the dosage used in the study, Xuong khop nam thang liquid extract showed analgesic and anti-inflammatory effects on experimental mice, the data was statistically significant with p < 0,05. The analgesic and anti-inflammatory effects are equivalent to the control drug group with p > 0,05.
Conclusion: Xuong khop nam thang liquid extract has analgesic and anti-inflammatory effects on experimental mice.
Article Details
Keywords
Xuong khop nam thang, pain relief, anti-inflammation.
References
2. Disease GBD, Injury I, Prevalence C. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the global burden of Disease study 2017. Lancet, 2018, Vol. 392, pp.1789-1858.
3. Woolfe G, Macdonald AD. The evaluation of the analgesic action of pethidine hydrochloride (demerol). Journal of Pharmacology and Experimental Therapeutics, 1944, Vol. 80, No. 3, pp.300-307.
4. Koster R, Anderson M, Debeer FJ. Acetic acid for analgetic screening, Fed. Proc, 1959, Vol. 18, pp.412.
5. Winter CA, Risley EA, Nuss GW. Carrageenin induced edema in hind paw of the rat as an assay for anti inflammatory drug. Proc, exp. Biol. NJ, 1962, Vol. 111, pp.544 - 574.
6. Ducrot R, Julon L, et al. Tumor screening methods in pharmacology. Academic press, 1965, pp.114 - 115.
7. Huỳnh Thị Kiều Nương. Nghiên cứu tác dụng giảm dau của bài thuốc Hoàng kỳ quế chi ngũ vật thang trên động vật thực nghiệm. Tạp chí Y học Việt Nam, 2022, Tập 519, số 2, tr.84-88.
8. Lê Tất Thành. Nghiên cứu độc tính bán trường diễn và tác dụng chống viêm của viên nang cứng “viên trĩ HV” trên động vật thực nghiệm, Luận văn thạc sĩ Y học cổ truyền, Học viện Y - Dược học cổ truyền Việt Nam, 2020.