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Date Published: 10/12/2024
Abstract Views: 37
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DOI: https://doi.org/10.60117/vjmap.v57i04.314
Issue
Vol. 57 No. 04 (2024)
Section
Research Articles
How to Cite
Đỗ, T. H., Đỗ, V. D., Nguyễn, V. H., Nguyễn, V. H., Lê, A. T., Hồ, M. D., Mai, P. T., Lê, A. T., Trần, T. T. T., Tô, T. T. P., Nguyễn, T. D., & Phan, H. M. (2024). Evaluating the anti-obesity effect of hot chili nanogel in mice. Viet Nam Journal of Traditional Medicine and Pharmacy, 57(04), 42-48. https://doi.org/10.60117/vjmap.v57i04.314

Evaluating the anti-obesity effect of hot chili nanogel in mice

Thị Hằng Đỗ, Văn Dũng Đỗ, Văn Hưng Nguyễn, Vũ Hùng Nguyễn, Anh Tuấn Lê, Mỹ Dung Hồ, Phương Thanh Mai, Anh Tùng Lê, Thị Thu Trang Trần, Thị Thanh Phương Tô, Thùy Dung Nguyễn, Hồng Minh Phan

Main Article Content

Abstract

Objectives: To evaluate the fat-dissolving and anti-obesity effect of topical chili nanogel of Capsicum annuum L in mice
Subjects and methods: This was an animal testing with control group. Swiss mice were obesity induced by a high-fat diet combined with oral olanzapine at a dose of 3 mg/kg continuously for 8 weeks. At the same time, all mice were randomly divided into 3 groups, including a biological control group, a model control group, and chili nanogel treatment group (with 0.15% of capsaicin) on the abdominal skin shaved continuously for 8 weeks.
Results: The chili nanogel of Capsicum annuum L applied to mice skin continously for 8 weeks could reduce weight gain and decrease BMI as well as reduced triglyceride levels in obese mice (p< 0.05), and tend to reduce visceral fat mass (p>0.05) in obese mice compared to the untreated model group.
Conclusions: The topical chili nanogel of Capsicum annuum L had an anti-obesity effect and improved lipid metabolic disorder in experimental animals.

Article Details

Keywords

Chili, pepper, capsaicin, Capsicum annuum L., obese mice

References

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