So sánh hiệu quả điều trị viêm mũi dị ứng của nhĩ áp kết hợp Fluticasone propionate với Fluticasone propionate đơn thuần

Abstract

Objectives: To compare the treatment efficacy of auricular acupressure combined with fluticasone propionate versus fluticasone propionate alone for allergic rhinitis.

Subjects and methods: A randomized, double-blind, controlled clinical trial study was conducted with 90 patients diagnosed with allergic rhinitis according to ARIA 2019 guidelines. The control group (n=45) received standard treatment, including lifestyle modifications, fluticasone propionate, and sham auricular acupressure, performed four times over four weeks. The intervention group (n=45) received standard treatment with actual auricular acupressure, performed four times over four weeks. Treatment efficacy was evaluated using a 100-mm visual analog scale (VAS) weekly and after four weeks of treatment, along with monitoring for adverse effects of auricular acupressure.

Results: The VAS scores for allergic rhinitis symptoms showed a statistically significant difference between the two groups after just one week of treatment (p<0.001). After four weeks, the reduction in VAS scores for individual symptoms, including sneezing, rhinorrhea, nasal congestion, and nasal itching, showed mean differences between the control and intervention groups of 17.71 (95% CI, 10.60–24.82); 22.73 (95% CI, 15.71–29.76); 22.33 (95% CI, 15.30–29.37); and 21.29 (95% CI, 14.27–28.31) points, respectively (p<0.0001). Adverse effects were reported in 11.11% of cases, mostly mild, transient, and not requiring additional treatment.

Conclusion: Auricular acupressure combined with fluticasone propionate provides effective and safe treatment for allergic rhinitis patients. Further interventional studies based on the classification of clinical syndromes in traditional medicine are warranted.