Nghiên cứu tác dụng giảm đau của bài thuốc Nhức mỏi trên thực nghiệm

Abstract

Objective: To evaluate the analgesic effects of the remedy "Thuoc nhuc moi” in experiments.

Subjects and methods: The analgesic effects of the remedy "Thuoc nhuc moi” were evaluated on 02 models inclucling tail immersion (central analgesic effect) and acetic acid intraperitoneal injection (peripheral analgesic effect) models.

Results: At doses of 9,18 and 36g (calculated by the amount of dry medicinal herbs)/kg/day x 5 consecutive days, the remedy “Thuoc Nhuc Moi” showed both central and peripheral analgesic effects on mice, in which the dose of 36g/kg/day revealed the best analgesic effect and was statistically higher than the other two doses (P values < 0.05). The analgesic effects of remedy “Thuoc Nhuc Moi” were less than that of codein phosphate at the dose of 20mg/ but similar to that of diclofenac sodium at the dose of 24mg/kg.

Conclusion: The remedy "Thuoc nhuc moi” has analgesic effects on experimental mice.