The Effeects Of Treatment Of Fatty Liver Disease On Experimental Animals
Main Article Content
Abstract
Objective: Evaluation of the effect of reducing liver fat in experimental animals.
Method: Study on experimental model of steatosis in rat liver. Results: Dosage of 1.2g/kg/day and 2.4g/ kg/day orally for 4 weeks improved liver fat in a white rat model of liver fat. Reduces total cholesterol, triglycerides in the blood and in the liver; decreases serum ALT and AST enzymes.
Article Details
Keywords
Gymnanthemum Amygdalinum, fatty liver disease, liver lipid.
References
1. Hoàng Trọng Thắng, (2014), Gan nhiễm mỡ, Giáo trình sau đại học- Bệnh tiêu hóa gan mật, NXB Đại học Huế, Huế, tr. 262- 276
2. Duarte, Márcia do Rocio, & Silva, Ariane Gonçalves. (2013). Anatomical characters of the medicinal leaf and stem of Gymnanthemum amygdalinum (Delile) Sch.Bip. ex Walp. (Asteraceae). Brazilian Journal of Pharmaceutical Sciences, 49(4), 719-727.
3. Ma, Z., Chu, L., Liu, H., Wang, W., Li, J., Yao, W., Yi, J., & Gao, Y. (2017). Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. Scientific reports, 7, 44819.
4. Rehm J, Samokhvalov AV, Shield KD. Global burden of alcoholic liver diseases. J Hepatol. 2013;59:160e168.
5. Jadeja, R. N., Devkar, R. V., & Nammi, S. (2017). Oxidative Stress in Liver Diseases: Pathogenesis, Prevention, and Therapeutics. Oxidative medicine and cellular longevity, 2017, 8341286.
2. Duarte, Márcia do Rocio, & Silva, Ariane Gonçalves. (2013). Anatomical characters of the medicinal leaf and stem of Gymnanthemum amygdalinum (Delile) Sch.Bip. ex Walp. (Asteraceae). Brazilian Journal of Pharmaceutical Sciences, 49(4), 719-727.
3. Ma, Z., Chu, L., Liu, H., Wang, W., Li, J., Yao, W., Yi, J., & Gao, Y. (2017). Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. Scientific reports, 7, 44819.
4. Rehm J, Samokhvalov AV, Shield KD. Global burden of alcoholic liver diseases. J Hepatol. 2013;59:160e168.
5. Jadeja, R. N., Devkar, R. V., & Nammi, S. (2017). Oxidative Stress in Liver Diseases: Pathogenesis, Prevention, and Therapeutics. Oxidative medicine and cellular longevity, 2017, 8341286.